Potential of Spider's Nest Extract Gel in Healing Traumatic Ulcers
Potensi Gel Ekstrak Sarang Laba-Laba dalam Penyembuhan Ulkus Traumatikus
Keywords:
spider egg nests, extract gel, healing process, traumatic ulcersAbstract
Background: Traumatic ulcer is an ulcerative lesion caused by trauma. One of the alternative natural materials that can be used for therapy is spider egg nests (Argiope modesta). Objective: To determine the potential of spider egg extract gel (Argiope modesta) in healing traumatic ulcers. Method: The research was conducted in a true experimental laboratory with a posttest only control group design. The research samples were 19 white Wistar rats (Rattus norvegicus). The samples were injured on the labial mucosa using an amalgam stopper heated for 10 seconds and then treated with 2.5% spider nest (Argiope modesta) egg extract gel. The size of the ulcer was measured every day before treatment was given using a caliper. Results: The independent t-test showed that the area of traumatic ulcers after being given 2.5% spider egg extract gel was significantly different (<0.05) compared to the negative control group with distilled water. Conclusion: Spider egg extract gel has the potential to accelerate the healing of traumatic ulcers.
References
Asparini, Ruby Riana. “Peran Heparin Dalam Angiogenesis, Epitelialisasi Dan Penyembuhan Luka Bakar.” Saintika Medika 7, no. 1 (2011).
Chun, Heung Jae, Kwideok Park, Chun-Ho Kim, dan Gilson Khang. Novel biomaterials for regenerative medicine. Springer, 2018.
Foelix, Rainer. Biology of spiders. OUP USA, 2011.
Gherunpong, Sudaduang, Georgios Tsakos, dan Aubrey Sheiham. “The Prevalence and Severity of Oral Impacts on Daily Performances in Thai Primary School Children.” Health and Quality of Life Outcomes 2, no. 1 (12 Oktober 2004): 57. https://doi.org/10.1186/1477-7525-2-57.
Ghom, Anil Govindrao, dan Savita Anil Ghom. Textbook of oral medicine. JP Medical Ltd, 2014.
Greenberg, M, dan M Click. “Burket’s Oral Medicine Hamilton.” Ontario: BC Decker Inc, 2003, 174–75.
Johnson, Ariel, Marybeth Francis, dan Luisa Ann DiPietro. “Differential apoptosis in mucosal and dermal wound healing.” Advances in wound care 3, no. 12 (2014): 751–61.
Kumari, Preeti, MK Chahar, VP Veerapur, G Spandana, BS Thippeswamy, dan S Badami. “Spider web ointment: A traditional based approach in cutaneous wound healing,” 2013.
Laskaris, G. Atlas Saku Penyakit Mulut. Jakarta: EGC, 2013.
Lewis, Michael A. O., dan Richard C. K. Jordan. “Penyakit Mulut: Diagnosis dan Terapi,” 2015. https://api.semanticscholar.org/CorpusID:198051714.
Makino, T., M. Jinnin, F. C. Muchemwa, S. Fukushima, H. Kogushi-Nishi, C. Moriya, T. Igata, A. Fujisawa, T. Johno, dan H. Ihn. “Basic Fibroblast Growth Factor Stimulates the Proliferation of Human Dermal Fibroblasts via the ERK1/2 and JNK Pathways.” The British Journal of Dermatology 162, no. 4 (April 2010): 717–23. https://doi.org/10.1111/j.1365-2133.2009.09581.x.
Ongole, Ravikiran, dan BN Praveen. Textbook of oral medicine, oral diagnosis and oral radiology e-book. Elsevier Health Sciences, 2021.
Roozbahani, Hassan, Mahdi Asmar, Naser Ghaemi, dan Khosro Issazadeh. “Evaluation of antimicrobial activity of spider silk Pholcus phalangioides against two bacterial pathogens in food borne.” International Journal of Advanced Biological and Biomedical Research 2, no. 7 (2014): 2197–99.
Senakoon, Waraluk, Suporn Nuchadomrong, Sivilai Sirimungkararat, Thanaset Senawong, dan Pravina Kitikoon. “Antibacterial action of eri (samia ricini) sericin against Escherichia coli and Staphylococcus aureus.” Asian J Food Agro-Ind 2 (2009): S222–28.
Xue, Rui, Yalong Liu, Qingsong Zhang, Congcong Liang, Huazhen Qin, Pengfei Liu, Ke Wang, Xiaoyong Zhang, Li Chen, dan Yen Wei. “Shape changes and interaction mechanism of Escherichia coli cells treated with sericin and use of a sericin-based hydrogel for wound healing.” Applied and environmental Microbiology 82, no. 15 (2016): 4663–72.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Al-Adawiyyah: Jurnal Sains, Farmasi dan Kesehatan

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

